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Vogelmeier CF, Criner GJ, Martinez FJ, et al

Check solubility: do not assume that a high-concentration stock will fully dissolve in water or DMSO

However, already at low doses, it appeared to influence control cells as well

Matrix metalloproteinases (MMPs) and their inhibitors, tissue inhibitors of metalloproteinases (TIMPs), are crucial in ECM remodeling, ensuring that the balance between synthesis and degradation of the matrix is maintained to support tissue repair and integrity