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When activated, the Nrf2 pathway upregulates the expression of a wide range of genes that help to protect cells against various stressors such as reactive oxygen species (ROS), electrophiles, and xenobiotics

Angiotensin-converting enzyme (ACE) inhibition is thought to be the primary mechanism underlying the blood pressure-lowering effects of several drugs, including those that affect the renin-angiotensin system (Yu et al., 2021)

Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes

Although phentermine is often labeled simply as an appetite suppressant, its true value extends beyond reducing hunger