Ku-70 Polyclonal Antibody, 100ul[BT-AP04894] Protein Post-translational Modification This gene is part of

This gene is part of a region that is repeated three times on chromosome X| once in intron 22 of the F8 gene and twice closer to the Xq telomere

Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres

The protein localizes to plasma membrane ruffles

where it regulates gene expression by phosphorylating

Ku-70 Polyclonal Antibody, 100ul[BT-AP04894] Protein Post-translational Modification This gene is part ofThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with