Gab 2(Phospho Tyr643) Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in this gene are

Mutations in this gene are associated with osteogenesis imperfecta types I-IV

one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation

Aberrant splice variants expressed in tumor cell lines have also been described

Transcripts from HIST1H3A lack polyA tails

Gab 2(Phospho Tyr643) Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in this gene areThis gene is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol 3 kinase in