SPB10 Polyclonal Antibody, 20ul Antibodies Mutations in this gene cause

Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID)

The protein encoded by this gene belongs to the glutathione peroxidase family| members of which catalyze the reduction of hydrogen peroxide| organic hydroperoxides and lipid hydroperoxides| and thereby protect cells against oxidative damage

This protein contains 6 WD repeats and is highly expressed in the heart

Interacts with bZIP transcription factors JUN

SPB10 Polyclonal Antibody, 20ul Antibodies Mutations in this gene causeThis gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer.