FAK Monoclonal Antibody, 100ul[BT-MCA0527] sgRNA Library Construction BCL2 family members form oligomers

BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities

Alternative splicing of this gene results in two transcript variants which encode the same protein

Inhibition of the encoded protein can lead to apoptosis

This gene encodes a gamma isoform of the regulatory subunit B55 subfamily

FAK Monoclonal Antibody, 100ul[BT-MCA0527] sgRNA Library Construction BCL2 family members form oligomersThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal