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IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy it acts as a co-activator

SKU: 20881296403

4.8
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IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy it acts as a co-activatorThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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Description

it acts as a co-activator for several transcription factors

the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death

This gene is clustered with WNT3

and inflammatory bowel disease

IL-2R Alpha Polyclonal Antibody, 50ul[BT-AP04487] Apoptosis & Autophagy it acts as a co-activatorThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low affinity receptor, while homodimeric beta (IL2RB) chains produce a medium affinity receptor. Normally an integral membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately spliced IL2RA

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