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However, a high level of extracellular glutamate occurs in the brain during epileptic seizures and is one of the causes of recurrent seizures

Signs and symptoms of overdosage reported with sulfonamides include anorexia, colic, nausea, vomiting, dizziness, headache, drowsiness and unconsciousness

This central action drastically decreases sympathetic outflow from the central nervous system to the heart, kidneys, and peripheral vasculature (Figure 1)(Patel and Saadabadi, 2025)

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