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Conversely, the metabolic journey of Treg cells carves a distinctive trail, with AMPK reigning as the chief metabolic maestro ( In T cells, the mTOR signaling axis serves as a regulatory hub, influencing various cellular mechanisms such as proliferation, programmed cell death, differentiation, and metabolic processes via activation of downstream transcriptional elements

Ethics The study protocol was approved by an independent ethics committee (Comitato Etico Cantonale, Canton Ticino, Switzerland)

That means results are gradual, cumulative , and depend heavily on consistency