EMR2 Polyclonal Antibody, 50ul[BT-AP02942] Lysosome and chondroitin-4

and chondroitin-4

mature peptide and a C-terminal propeptide

The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells

A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus

EMR2 Polyclonal Antibody, 50ul[BT-AP02942] Lysosome and chondroitin-4ADGRE2 encodes a member of the class B seven span transmembrane (TM7) subfamily of G protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor like domains coupled to a TM7 domain via a mucin like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell cell adhesion through interaction with chondroitin sulfate