PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 50ul Bacterial Expression Mutations in TUBA1A cause lissencephaly

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

extracellular collagenous domain

The product of ITGAV belongs to the integrin alpha chain family

This gene encodes a member of the POU domain family of transcription factors

PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 50ul Bacterial Expression Mutations in TUBA1A cause lissencephalyThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in