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GIP Agonism Reduces appetite, nausea, and bone resorption Increases insulin & glucagon production, and lipogenesis Glucagon Agonism Reduces appetite, food intake, and gastric emptying Increases insulin production, energy expenditure, and nausea Amylin Agonism Reduces appetite, food intake, glucagon production, and gastric emptying Increases energy expenditure Reduces bone resorption and increases bone production PYY Agonism Reduces appetite, food intake, and gastric emptying Increases energy expenditure and nausea The Cost Challenge for Payers The cost of GLP-1s continues to be a significant concern for payers between skyrocketing costs and utilization over the past several years

The hydrogel eye mask patch provides a cooling effect upon application, reducing skin temperature while promoting absorption of active ingredients deep into the skin

The company focuses specifically on compounded GLP-1 medications, primarily compounded semaglutide with B6 and compounded tirzepatide with B6

Lipofectamine 2000 (batch number 11668500) was purchased from Thermo Fisher