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And although he says that individuals generally dont experience sleep problems in the absence of supplementation, he recommends that users take a night off from sleep supplements every month or so to understand where you might have developed a dependency, either real or placebo-based, on these sleep supplements. Hormone Support When it comes to supplementation for hormone support, Huberman reiterates the fact that behavioral and nutritional protocols come first

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Patient compliance advantage frequently compensates for the bioavailability gap