RGMC Polyclonal Antibody, 100ul Thermo Mix Nuclear pore complex protein Nup88

Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex

migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance

and a carboxy-terminal non-collagenous domain

and plays a regulatory role in S phase DNA replication and DNA damage repair

RGMC Polyclonal Antibody, 100ul Thermo Mix Nuclear pore complex protein Nup88The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in