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Description

Gastrointestinal adverse events affected 79.6% of the CagriSema group in REDEFINE 1, compared to 39.9% with placebo

At 40 degrees Celsius (a hot car on a mild day), the reaction rate roughly quadruples compared to refrigerated conditions

Appetite may increase, cravings may return and previous patterns may reappear

Liraglutide and tirzepatide work through similar appetite- and digestion-regulating pathways and share many of the same side effects, including nausea, vomiting, diarrhea, and constipation