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Critically, our use of a single base medium is a key advantage that paves the way for future studies on multitissue coculture platforms designed to unravel the complex interorgan communication that governs systemic metabolism

For many people taking drugs like tirzepatide or semaglutide, losing weight isnt the hardest part

In clinical trials of ROSE-010 for IBS, the greatest pain reductions were seen in IBS-M and IBS-C groups , implying that those with mixed symptoms can gain significant relief in abdominal pain and cramping from GLP-1 activation

However, due to the paucity of data, observed differences in efficacy cannot be generalized to patients affected by overweight (that is, with BMI 2730 kg m 2 ) or to those with a BMI 40 kg m 2