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doi: 10.3389/fphar.2025.1660109 Received 05 July 2025 Accepted 01 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Ernesto Satoshi Nakayasu, Pacific Northwest National Laboratory (DOE), United States Reviewed by Wenlong Sun, Shandong University of Technology, China Jiayu Wang, Capital Medical University, China Updates Copyright 2025 Zhang, Wu, Chen, Liu, Li and Chen