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We investigated glutathione redox balance, H 2 S levels, oxidative stress, the opening of the mitochondrial permeability transition pore (mPTP), the resistance of isolated heart to ischemia/reperfusion in Langendorff model, endothelium-dependent vasorelaxation of isolated aortic rings, and cardiac levels of 3-MST , CSE , and UCP3 mRNA were determined using real-time PCR analysis