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doi: 10.1136/bmjdrc-2021-002300 23 FunchDMortimerKZiyadehNJSeegerJZhouLNgEet al

Structurally, semaglutide is similar to liraglutide but with two key modifications - replacement of glycine at position 8 with alpha-aminoisobutyric acid and optimization of the fatty acid chain for albumin binding