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This suggests a potential synergistic effect of Se and vitamin D in improving cognitive function, whereby Se may positively influence cognition by modulating vitamin D levels (318)

10.1002/mrm.1910300604 40

10.1016/j.tibs.2018.05.003 127 KeshetR.SzlosarekP.CarracedoA.ErezA

In patients already receiving an opioid analgesic, prescribe a lower initial dose of the benzodiazepine or other CNS depressant than indicated in the absence of an opioid, and titrate based on clinical response