sitaxsentan Size:Solid 10 mg CDK8/19i is a potent and

CDK8/19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2

Chemical Name: (E)-(2-aminoethoxy)({5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene})amine

(2015) J Med Chem

inhibition of cell proliferation

sitaxsentan Size:Solid 10 mg CDK8/19i is a potent andSitaxentan, also known as TBC 11251 and IPI 1040, is a medication for the treatment of pulmonary arterial hypertension (PAH). It was marketed as Thelin. In 2010, Pfizer voluntarily removed sitaxentan from the market due to concerns about liver toxicity. Sitaxentan is a small molecule that blocks the action of endothelin (ET) on the endothelin A (ETA) receptor selectively (by a factor of 6000 compared with the ETB). Product information CAS Number: