SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter the N-terminal regulatory domain that

the N-terminal regulatory domain that is processed upon calpain activation

Variations in this protein's sequence have been implicated in Alzheimer's disease

or changes in metabolism

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA

SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter the N-terminal regulatory domain thatThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.