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Advances in Gerontology, 2007, Volume 20 (Issue 1), Pages 74-85

More often, its downstream of something else: Hormonal changes perimenopause, postpartum recovery, low testosterone, estrogen dominance Thyroid dysfunction (which is why we run four thyroid markers, not one) Insulin resistance and elevated fasting insulin, often years before blood sugar shows up as abnormal Chronic inflammation, gut issues, or nutrient deficiencies (vitamin D and B12 are common offenders) Cortisol and sleep disruption a real factor for new moms, shift workers, and high-stress professionals A GLP-1 wont fix any of those

Compton, C

A successful intervention strategy must be layered, addressing both upstream triggers and downstream consequences