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Phase 2 dose-finding trial Published in The Lancet in 2021, this multicenter, randomized, double-blind trial tested cagrilintide doses ranging from 0.3 mg to 4.5 mg weekly in people with overweight or obesity

Since the enzyme preparation required the GSH-peroxide system for its catalytic activity, it was termed GPx

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Multiple studies have clearly shown that markers of oxidative stress such as malondialdehyde (MDA), superoxide dismutase (SOD) and lipid peroxidation byproduct levels are elevated in patients suffering from major depressive disorder (Sarandol et al., 2007