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These include PTU, which was thought to decrease the hypermetabolic state induced by alcohol

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A Phase 2 trial testing an HDT alongside standard TBM antibiotics could in principle move faster than if these drugs had to clear the full de novo safety pipeline first, as noted in a 2025 European Journal of Medical Research review of host-directed TB therapies

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If your clinician has concerns, they will contact you in the HIPAA-compliant patient portal

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These observations underscore the importance of validating preclinical discoveries in patient-derived models and incorporating biomarker-driven stratification into clinical trial designs to ensure that therapeutic strategies are both effective and broadly applicable

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