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The peptide itself is essentially a copper-delivery vehicle, without intact Cu coordination (color check: deep blue), the molecule loses most of its biological activity

GHK-Cu was also shown to play a role in ischemic and diabetic wound healing in rats, as well as decreasing TNF-alpha levels and increasing collagen synthesis ( Anti-Inflammatory Effects of GHK-Cu As it was mentioned above, GHK-Cu is shown to have antioxidant and anti-inflammatory properties

Further, a secondary analysis of a trial in women at high risk for or with existing cardiovascular disease reported that high-dose supplemental B-vitamins (1 mg/day of vitamin B 12 , 50 mg/day of vitamin B6, and 2.5 mg/day of folic acid) for 7.3 years had no effect on risk of non-vertebral fractures (122)

Xie et al., 2024)