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Involvement of ERK1/2 pathway in BPC-157-induced cell proliferation, migration, and tube formation To explore whether the ERK1/2, JNK, or p38 pathway was involved in BPC-157-induced cell proliferation, migration, and tube formation, PD98059 (ERK1/2 inhibitor), SP600125 (JNK inhibitor), and SB203580 (p38 inhibitor) were used

A., Gruber, K

Trial STEP 2 (Davies et al., Lancet 2021) Design Phase 3 / 68 weeks Population 1,210 adults with T2D and overweight or obesity Key result -9.6% body weight (2.4 mg) vs -3.4% placebo