SPI2 Polyclonal Antibody, 50ul Vacuum Aspirator Diseases associated with IGHG1 include

Diseases associated with IGHG1 include chronic lymphocytic leukemia and heavy chain deposition disease

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases

Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility

SPI2 Polyclonal Antibody, 50ul Vacuum Aspirator Diseases associated with IGHG1 includeThe gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene.