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Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment Female mice lacking ZP2 (zona

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Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment Female mice lacking ZP2 (zonaThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

Female mice lacking ZP2 (zona pellucida glycoprotein 2) do not form a stable zona matrix and are sterile

migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors

The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity

Ku-70 Polyclonal Antibody, 50ul[BT-AP04897] In vitro Assessment Female mice lacking ZP2 (zonaThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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