Genz-644282 icheliolide Buparlisib
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Genz-644282 icheliolide BuparlisibGenz 644282, also known as SAR402674, is a non camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz 644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations. Product information CAS Number: 529488 28 6 Molecular Weight: 407. 42 Formula:
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