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You can read the full article at Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity The objective of this study was to evaluate the long-term effectiveness and safety of pramlintide, a medication used for weight loss, in combination with a lifestyle intervention program (LSI).In a 4-month study, 411 obese participants were randomly assigned to receive different doses of pramlintide or a placebo, along with the LSI program