Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 20ul[BT-AP04537] Serological Pipets NODAL (nodal growth differentiation factor)

NODAL (nodal growth differentiation factor) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

transmembrane receptor protein which may function in angiogenesis

and downregulation of this gene may play a role in breast cancer

Methylation of the genes promoter has been associated with several cancer types

Rpb1 CTD(Phospho-Thr4) Rabbit Polyclonal Antibody, 20ul[BT-AP04537] Serological Pipets NODAL (nodal growth differentiation factor)This gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase