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Tesofensine lowers body weight mainly by reducing appetite, increasing satiety, and enhancing energy expenditure, making it a promising candidate for the pharmacological treatment of obesity 1-4

But as a good practice, maintain hydration and adequate protein intake

Seasonal considerations Some researchers align their epitalon cycles with seasonal transitions, particularly the shift into winter when natural melatonin production changes and circadian disruption becomes more common

doi:10.1016/j.scitotenv.2014.03.089 Moore DE, Chappuis PP (1988) A comparative study of the photochemistry of the non-steroidal anti-inflammatory drugs, naproxen, benoxaprofen and indomethacin