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GPX1 is one of the most abundant members of the GPX family of enzymes

Ascorbate is then regenerated by the selenoenzyme thioredoxin reductase

The mitochondrial DOX-Fe 2+ complex induces triggers lipid peroxidation, resulting in mitochondria-dependent ferroptosis and decreased cardiac function in mice, which is reflected in significantly reduced left ventricular ejection fraction and myocardial fibrosis

te yandan kilo verme konusundaki etkilerine dair meta-analizlerde bildirilen sonular minimal dzeyde olduundan ve yukarda bahsettiimiz baz risk ve yan etkilerinden dolay yazarlar normal bir beslenme ve egzersiz dzeni ile kilo vermeye almann daha uygun bir seenek olduunu belirtmilerdir (27)